Medications and Drugs
Brand Names: Angeliq
Generic Name: drospirenone and estradiol (Pronunciation: droe SPYE re none and ES tra DYE ole)
What is drospirenone and estradiol (Angeliq)?
Drospirenone is a female hormone that helps regulate ovulation and menstruation.
Estradiol is a female hormone involved in development and maintenance of the female reproductive system.
The combination of drospirenone and estradiol is used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. This medication is for use only if you have a uterus (if you have not had a hysterectomy).
Drospirenone and estradiol may also be used for purposes not listed in this medication guide.
What are the possible side effects of drospirenone and estradiol (Angeliq)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using drospirenone and estradiol and call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about drospirenone and estradiol (Angeliq)?
Do not use drospirenone and estradiol if you are pregnant or plan to become pregnant.
You should not take this medicine if you have any of the following conditions: a bleeding or blood-clotting disorder, circulation problems, unusual vaginal bleeding, kidney disease, liver disease, an adrenal gland disorder, if you have had a hysterectomy, if you have had a heart attack a stroke, or if you have ever had breast or uterine cancer, or a blood clot (especially in your lung or your lower body).
Smoking can increase your risk of blood clots, stroke, or heart attack caused by birth control pills, especially if you are older than 35. Drospirenone may be more likely to cause blood clots than other types of female hormone medication.
Stop using drospirenone and estradiol and call your doctor at once if you have chest pain, sudden numbness or weakness, a sudden severe headache, confusion, problems with vision or speech, or if you have pain, swelling, warmth, or redness in one or both legs.
Call your doctor right away if you have a breast lump, unusual vaginal bleeding, or jaundice (yellowing of the skin or eyes).
Drospirenone and estradiol should not be used to prevent heart disease, stroke, or dementia, because this medicine may actually increase your risk of developing these conditions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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