drospirenone and estradiol (cont.)
What happens if I miss a dose (Angeliq)?
If you are less than 24 hours late in taking your medicine, take the missed dose as soon as you remember. Skip the missed dose if it is time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Angeliq)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe nausea or vaginal bleeding.
What should I avoid while taking drospirenone and estradiol (Angeliq)?
Smoking can increase your risk of blood clots, stroke, or heart attack caused by birth control pills, especially if you are older than 35. Drospirenone may be more likely to cause blood clots than other types of female hormone medication.
Avoid drinking alcohol while you are taking this medication.
Grapefruit and grapefruit juice may interact with drospirenone and estradiol and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.
What other drugs will affect drospirenone and estradiol (Angeliq)?
Tell your doctor about all other medicines you use, especially:
- eplerenone (Inspra);
- ritonavir (Norvir, Kaletra);
- St. John's wort;
- an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or rifampin (Rifater, Rifadin, Rifamate);
- an antifungal medication such as ketoconazole (Nizoral) or itraconazole (Sporanox);
- aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;
- a blood thinner such as warfarin (Coumadin, Jantoven);
- a diuretic ("water pill") such as spironolactone (Aldactone), triamterene (Dyrenium, Dyazide, Maxzide), amiloride (Midamor), or eplerenone (Inspra);
- heart or blood pressure medications such as benazepril (Lotensin), candesartan (Atacand), enalapril (Vasotec), fosinopril (Monopril), irbesartan (Avapro, Avalide), lisinopril (Prinivil, Zestril), losartan (Cozaar, Hyzaar), olmesartan (Benicar), ramipril (Altace), valsartan (Diovan), telmisartan (Micardis);
- a potassium supplement such as Klor-Con, K-Dur, K-Tab; or
- seizure medications such as carbamazepine (Carbatrol, Equetro, Tegretol) or phenobarbital (Solfoton).
This list is not complete and other drugs may interact with drospirenone and estradiol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about drospirenone and estradiol.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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