duloxetine (cont.)

What is duloxetine (Cymbalta)?
What are the possible side effects of duloxetine (Cymbalta)?
What is the most important information I should know about duloxetine (Cymbalta)?
What should I discuss with my healthcare provider before taking duloxetine (Cymbalta)?
How should I take duloxetine (Cymbalta)?
What happens if I miss a dose (Cymbalta)?
What happens if I overdose (Cymbalta)?
What should I avoid while taking duloxetine (Cymbalta)?
What other drugs will affect duloxetine (Cymbalta)?
Where can I get more information?

What happens if I miss a dose (Cymbalta)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Cymbalta)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include agitation, hallucinations, fever, overactive reflexes, loss of coordination, extreme drowsiness, vomiting, diarrhea, seizure (convulsions), fast heart rate, feeling light-headed, or fainting.

What should I avoid while taking duloxetine (Cymbalta)?

Avoid drinking alcohol. It may increase your risk of liver damage.

Duloxetine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What other drugs will affect duloxetine (Cymbalta)?

Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with duloxetine may cause you to bruise or bleed easily.

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, or anxiety can add to sleepiness caused by duloxetine. Tell your doctor if you regularly use any of these medicines, or any other antidepressant.

Tell your doctor about all other medicines you use, especially:

a blood thinner such as warfarin (Coumadin);
cimetidine (Tagamet);
a diuretic (water pill);
fluvoxamine (Luvox);
linezolid (Zyvox);
lithium (Lithobid, Eskalith);
St. John's wort;
tramadol (Ultram);
tryptophan (sometimes called L-tryptophan);
an antibiotic such as ciprofloxacin (Cipro);
almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); or
any other antidepressant such as desipramine (Norpramin), fluoxetine (Prozac, Sarafem), paroxetine (Paxil), and others.

This list is not complete and other drugs may interact with duloxetine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about duloxetine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 9.01. Revision date: 6/12/2011.
Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link.