What happens if I miss a dose (Cymbalta)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Cymbalta)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include agitation, hallucinations, fever, overactive reflexes, loss of coordination, extreme drowsiness, vomiting, diarrhea, seizure (convulsions), fast heart rate, feeling light-headed, or fainting.
What should I avoid while taking duloxetine (Cymbalta)?
Avoid drinking alcohol. It may increase your risk of liver damage.
Duloxetine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
What other drugs will affect duloxetine (Cymbalta)?
Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with duloxetine may cause you to bruise or bleed easily.
Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, or anxiety can add to sleepiness caused by duloxetine. Tell your doctor if you regularly use any of these medicines, or any other antidepressant.
Tell your doctor about all other medicines you use, especially:
- a blood thinner such as warfarin (Coumadin);
- cimetidine (Tagamet);
- a diuretic (water pill);
- fluvoxamine (Luvox);
- linezolid (Zyvox);
- lithium (Lithobid, Eskalith);
- St. John's wort;
- tramadol (Ultram);
- tryptophan (sometimes called L-tryptophan);
- an antibiotic such as ciprofloxacin (Cipro);
- almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); or
- any other antidepressant such as desipramine (Norpramin), fluoxetine (Prozac, Sarafem), paroxetine (Paxil), and others.
This list is not complete and other drugs may interact with duloxetine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about duloxetine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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