What happens if I miss a dose (Cymbalta)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Cymbalta)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking duloxetine (Cymbalta)?
Avoid drinking alcohol. It may increase your risk of liver damage.
Duloxetine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
What other drugs will affect duloxetine (Cymbalta)?
Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin, piroxicam, nabumetone, etodolac, and others. Taking any of these drugs with duloxetine may cause you to bruise or bleed easily.
Taking duloxetine with other drugs that make you sleepy or slow your breathing can increase these effects. Ask your doctor before taking duloxetine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Many drugs can interact with duloxetine. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with duloxetine, especially:
- a blood thinner such as warfarin, Coumadin;
- a diuretic or "water pill";
- St. John's wort;
- tryptophan (sometimes called L-tryptophan);
- an antibiotic such as ciprofloxacin;
- almotriptan, frovatriptan, sumatriptan, naratriptan, rizatriptan, or zolmitriptan; or
- any other antidepressant such as desipramine, fluoxetine, fluvoxamine, paroxetine, and others.
This list is not complete and many other drugs can interact with duloxetine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about duloxetine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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