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What should I discuss with my health care provider before receiving edrophonium (Enlon, Tensilon)?

You should not receive this medication if you are allergic to edrophonium, or have certain conditions. Be sure your doctor knows if you have:

• a blockage in your intestines; or
• obstructed urine flow.

Before you receive edrophonium, tell your doctor if you are allergic to any drugs, or if you have:

• asthma;
• a heart rhythm disorder; or
• if you are allergic to sulfites.

If you have any of these conditions, you may need a dose adjustment or special tests to safely receive edrophonium.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant before you receive edrophonium.

Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is edrophonium given (Enlon, Tensilon)?

Edrophonium is given as an injection through a needle placed into a muscle or vein. You will receive this injection in a clinic or hospital setting as part of a medical test.

When used in diagnosing myasthenia gravis, edrophonium is given in small doses over 15 to 45 seconds. After each dose you will be observed for the expected reaction to this medication (muscle twitching, vision changes, increased muscle weakness, sweating, stomach cramps, nausea, and other symptoms). You may receive other medications to treat the reaction to edrophonium.

The test you are receiving may be repeated a second time.

Your specific edrophonium test may be performed in a different manner than described above.

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