Medications and Drugs
Brand Names: Inspra
Generic Name: eplerenone (Pronunciation: ep LER e none)
What is eplerenone (Inspra)?
Eplerenone blocks the actions of the hormone aldosterone in the body. Aldosterone is important for the regulation of blood pressure.
Eplerenone may also be used for other purposes not listed in this medication guide.
Eplerenone 25 mg-APO
round, yellow, imprinted with APO, EP 25
Eplerenone 50 mg-APO
round, yellow, imprinted with APO, EP 50
Inspra 25 mg
diamond, yellow, imprinted with Pfizer, NSR 25
Inspra 50 mg
diamond, pink, imprinted with Pfizer, NSR 50
What are the possible side effects of this drug (Inspra)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about eplerenone (Inspra)?
You also may not be able to take eplerenone if you are also taking ketoconazole (Nizoral), itraconazole (Sporanox), nefazodone, clarithromycin (Biaxin), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), or troleandomycin (Tao).
Do not use salt substitutes or potassium supplements while taking eplerenone, unless your doctor has told you to.
To be sure this medication is helping your condition and is not causing harmful effects, your blood pressure will need to be checked on a regular basis. Your potassium levels will also need to be checked with frequent blood tests. Do not miss any scheduled appointments.
Keep using this medicine as directed, even if you feel well. Hypertension often has no symptoms, so you may not know when your blood pressure is high.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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