estradiol and norethindrone (topical patches) (cont.)
IN THIS ARTICLE
What happens if I miss a dose (Combipatch)?
Apply the next patch as soon as you remember. Continue to follow your regular schedule for changing the patch. Do not use two patches simultaneously unless your doctor directs otherwise.
If a patch falls off for any reason, reapply it to another site on your lower abdomen. If it will not stick, apply a new patch to a new site. Continue changing the patch on your regular schedule.
What happens if I overdose (Combipatch)?
An overdose of estradiol and norethindrone is unlikely to occur and is not likely to threaten life. If you do suspect an overdose, or if a patch has been ingested, call an emergency room or poison control center for advice.
Symptoms of a estradiol and norethindrone overdose may include nausea, vomiting, and withdrawal bleeding may occur in females.
What should I avoid while using estradiol and norethindrone (Combipatch)?
After a patch is in place, it should not be exposed the sun for prolonged periods of time.
There are no restrictions on food, beverages, or activity while using estradiol and norethindrone unless your doctor directs otherwise.
What other drugs will affect estradiol and norethindrone (Combipatch)?
Before using estradiol and norethindrone, tell your doctor if you are taking an anticoagulant (blood thinner) such as warfarin (Coumadin). You may not be able to use estradiol and norethindrone, or you may require a dosage adjustment or special monitoring during treatment if you are taking warfarin (Coumadin).
Drugs other than those listed here may also interact with estradiol and norethindrone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.
Where can I get more information?
Your pharmacist has additional information about estradiol and norethindrone written for health professionals that you may read.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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