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Medications and Drugs

Brand Names: Corifact

Generic Name: factor XIII (Pronunciation: FAK tor 13 (thirteen))

What is factor XIII (Corifact)?

Factor XIII is used to prevent bleeding episodes in people with a hereditary bleeding disorder caused by a deficiency of Factor XIII.

Factor XIII will not treat a bleeding episode that has already begun.

Factor XIII may also be used for purposes not listed in this medication guide.

What are the possible side effects of factor XIII (Corifact)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • new or worsening bleeding episodes;
  • unusual bruising;
  • sudden numbness or weakness, especially on one side of the body;
  • sudden severe headache, confusion, problems with vision, speech, or balance;
  • chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or
  • pain, swelling, warmth, or redness in one or both legs.

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about factor XIII (Corifact)?

You should not use this medication if you are allergic to factor XIII or to any medicine made with human plasma.

Before using factor XIII, tell your doctor if you have liver disease.

You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

Call your doctor at once if you have new or worsening bleeding episodes, sudden numbness or weakness, chest pain, coughing up blood, problems with vision or speech, or pain, swelling, warmth, or redness in one or both legs.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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