factor XIII (cont.)
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What should I discuss with my healthcare provider before taking factor XIII (Corifact)?
You should not use this medication if you are allergic to factor XIII or to any medicine made with human plasma.
To make sure you can safely take factor XIII, tell your doctor if you have liver disease.
FDA pregnancy category C. It is not known whether factor XIII will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether factor XIII passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Factor XIII is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
How should I take factor XIII (Corifact)?
Factor XIII is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Factor XIII is usually given once every 4 weeks. Follow your doctor's dosing instructions very carefully.
Factor XIII is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.
Allow the mixture to reach room temperature before giving the injection. Do not heat the medicine before using.
Factor XIII should look clear or slightly yellow in color. Do not use the medication if it has changed colors or has particles in it. Call your doctor for a new prescription.
Do not mix factor XIII with other injectable medications in the same IV line.
Each single use vial (bottle) of this medicine is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose.
To be sure this medication is helping your condition, your blood may need to be tested often. Visit your doctor regularly.
Store unmixed factor XIII in the refrigerator, do not freeze. Keep the medicine in its original container.
Unopened vials of factor XIII may also be stored at room temperature for up to 6 months, away from moisture, heat, and light. Do not refrigerate an unopened vial that has been stored at room temperature.
Throw away any unused factor XIII after the expiration date on the label has passed.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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