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Brand Names: Uloric

Generic Name: febuxostat (Pronunciation: fe BUX oh stat)

• What is febuxostat (Uloric)?
• What are the possible side effects of febuxostat (Uloric)?
• What is the most important information I should know about febuxostat (Uloric)?
• What should I discuss with my healthcare provider before taking febuxostat (Uloric)?
• How should I take febuxostat (Uloric)?
• What happens if I miss a dose (Uloric)?
• What happens if I overdose (Uloric)?
• What should I avoid while taking febuxostat (Uloric)?
• What other drugs will affect febuxostat (Uloric)?
• Where can I get more information?

What is febuxostat (Uloric)?

Febuxostat reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones.

Febuxostat is used to treat gout.

Febuxostat may also be used for purposes not listed in this medication guide.

What are the possible side effects of febuxostat (Uloric)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
• sudden numbness or weakness, especially on one side of the body;
• sudden headache, confusion, problems with vision, speech, or balance; or
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

• nausea;
• joint pain, swelling, or stiffness;
• mild skin rash; or
• dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about febuxostat (Uloric)?

You should not use this medication if you are allergic to febuxostat, or if you are also being treated with azathioprine (Azasan, Imuran), mercaptopurine (Purinethol), or theophylline (Elixophyllin, TheoCap, Theochron, Uniphyl).

Before taking febuxostat, tell your doctor if you have kidney disease, liver disease, heart disease, cancer, Lesch-Nyhan syndrome, a history of heart attack or stroke, or if you have ever received an organ transplant.

You may have an increase in gout symptom flares when you first start taking febuxostat. For best results, keep taking the medication as directed. Your doctor may prescribe other gout medications for you to use during the first 6 months of treatment with febuxostat.

To be sure this medication is helping your condition, your blood may need to be tested often. Visit your doctor regularly.

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