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Medications and Drugs

Brand Names: Artiss, Artiss Duo Set, Artiss Duploject, Tisseel, Tisseel Duploject Kit, Tisseel Valupak Kit

Generic Name: fibrin sealant topical (Pronunciation: FYE brin SEE lant TOP i kal)

What is fibrin sealant topical (Artiss, Artiss Duo Set, Artiss Duploject, Tisseel, Tisseel Duploject Kit, Tisseel Valupak Kit)?

Fibrinolysis inhibitor and thrombin are agents that are involved in blood clotting.

Fibrin sealant topical is used to cause blood clotting during surgery or due to trauma when natural blood clotting processes are deficient.

Fibrin sealant topical may also be used for purposes other than those listed here.

What are the possible side effects of fibrin sealant topical?

Fibrin sealant topical is made from human plasma (part of the blood) and may contain infectious agents (e.g., viruses) that can cause disease. Although fibrin sealant topical is screened, tested, and treated to reduce the possibility that it carries an infectious agent, it can still potentially transmit disease. Discuss with your doctor the risks and benefits of using fibrin sealant topical.

Contact your doctor if you develop fever, drowsiness, chills, runny nose, rash, joint pain, poor appetite, tiredness, nausea, vomiting, abdominal pain, dark-colored urine, or yellowing of the skin or eyes following treatment with fibrin sealant topical. These may be symptoms of infections that may occur due to use of this product.

Notify your doctor immediately if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to fibrin sealant topical.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about fibrin sealant topical?

Fibrin sealant topical is made from human plasma (part of the blood) and may contain infectious agents (e.g., viruses) that can cause disease. Although fibrin sealant topical is screened, tested, and treated to reduce the possibility that it carries an infectious agent, it can still potentially transmit disease. Discuss with your doctor the risks and benefits of using fibrin sealant topical.

Contact your doctor if you develop fever, drowsiness, chills, runny nose, rash, joint pain, poor appetite, tiredness, nausea, vomiting, abdominal pain, dark-colored urine, or yellowing of the skin or eyes following treatment with fibrin sealant topical. These may be symptoms of infections that may occur due to use of this product.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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