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What should I discuss with my healthcare provider before taking flucytosine (Ancobon)?

Before taking flucytosine, tell your doctor if you

• have kidney disease,
• have a blood or bone marrow disease, or
• are being treated with radiation or a drug that causes bone marrow suppression.

You may not be able to take flucytosine or you may need a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Flucytosine is in the FDA pregnancy category C. This means that it is not known whether flucytosine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether flucytosine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take flucytosine (Ancobon)?

Take flucytosine exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass (8 ounces) of water.

Flucytosine may cause nausea and vomiting. You can reduce this side effect by taking the capsules a few at a time over a 15-minute period. Notify your doctor if nausea and vomiting become unbearable.

Take all of the flucytosine that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.

It is important to take flucytosine regularly to get the most benefit.

Your doctor may want you to have blood tests or other medical evaluations during treatment with flucytosine to monitor progress and side effects.

Store this medication at room temperature away from moisture and heat.

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