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What happens if I miss a dose (Symbyax)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Symbyax)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include some of the serious side effects listed in this medication guide.

What should I avoid while taking fluoxetine and olanzapine (Symbyax)?

Drinking alcohol can increase certain side effects of fluoxetine and olanzapine.

Fluoxetine and olanzapine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What other drugs will affect fluoxetine and olanzapine (Symbyax)?

Ask your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with fluoxetine and olanzapine may cause you to bruise or bleed easily.

Before using fluoxetine and olanzapine, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety). They can add to sleepiness caused by fluoxetine and olanzapine.

Tell your doctor about all other medicines you use, especially:

• vinblastine (Velban);
• heart rhythm or blood pressure medication;
• tryptophan (sometimes called L-tryptophan);
• lithium, clozapine (Clozaril, Fazaclo), haloperidol (Haldol);
• phenytoin (Dilantin), carbamazepine (Carbatrol, Tegretol);
• a blood thinner such as warfarin (Coumadin, Jantoven);
• theophylline (Elixophyllin, Theo-24, Theochron, Uniphyl, and others);
• medicine to treat Parkinson's disease, such as bromocriptine (Parlodel), pergolide (Permax), pramipexole (Mirapex), ropinorole (Requip), or cabergoline (Cabaser);
• almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex, Treximet), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); or
• any other antidepressants, especially another form of fluoxetine or olanzapine such as Prozac, Prozac Weekly, Sarafem, or Zyprexa.

This list is not complete and other drugs may interact with fluoxetine and olanzapine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about fluoxetine and olanzapine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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