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What should I discuss with my healthcare provider before taking flurbiprofen (Ansaid)?

This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term. Do not use flurbiprofen just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking flurbiprofen, especially in older adults.

Do not use this medication if you are allergic to flurbiprofen, or if you have:

• severe kidney disease; or
• a history of allergic reaction to aspirin or other NSAIDs.

If you have any of these other conditions, you may need a flurbiprofen dose adjustment or special tests:

• a history of heart attack, stroke, or blood clot;
• heart disease, congestive heart failure, high blood pressure;
• a history of stomach ulcer or bleeding;
• liver or kidney disease;
• asthma;
• polyps in your nose;
• a bleeding or blood clotting disorder; or
• if you smoke.

FDA pregnancy category C. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking flurbiprofen during the last 3 months of pregnancy may harm the unborn baby. Do not take flurbiprofen during pregnancy unless your doctor has told you to.

Flurbiprofen can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medicine to a child without the advice of a doctor.

How should I take flurbiprofen (Ansaid)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

The maximum amount of flurbiprofen for adults is 400 milligrams (mg) per day. Know the amount of flurbiprofen in the specific product you are taking.

If you take flurbiprofen for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled appointments.

Store at room temperature, away from moisture, heat, and light.

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