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Brand Names: Eulexin

Generic Name: flutamide (oral) (Pronunciation: FLEW ta mide)

• What is flutamide (Eulexin)?
• What are the possible side effects of flutamide (Eulexin)?
• What is the most important information I should know about flutamide (Eulexin)?
• What should I discuss with my healthcare provider before taking flutamide (Eulexin)?
• How should I take flutamide (Eulexin)?
• What happens if I miss a dose (Eulexin)?
• What happens if I overdose (Eulexin)?
• What should I avoid while taking flutamide (Eulexin)?
• What other drugs will affect flutamide (Eulexin)?
• Where can I get more information?

What is flutamide (Eulexin)?

Flutamide is an antiandrogen. It works in the body to prevent the actions of androgens (male hormones).

Flutamide is used in the treatment of prostate cancer.

Flutamide may also be used for purposes other than those listed in this medication guide.

Flutamide 125 mg-BAR

brown/white, imprinted with barr, 870

Flutamide 125 mg-IVA

beige, imprinted with Hourglass Logo 4960

What are the possible side effects of flutamide (Eulexin)?

Stop taking flutamide and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

In rare cases, flutamide has caused severe liver damage resulting in death or hospitalization. Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, "flu-like" symptoms, yellow skin or eyes, itching, clay-colored stools, or dark urine. These symptoms may be early signs of liver damage.

Other, less serious side effects may be more likely to occur. Continue to take flutamide and talk to your doctor if you experience

• hot flashes,
• diarrhea,
• skin rash,
• increased skin sensitivity to sunlight,
• loss of sex drive,
• impotence,
• lowered sperm count,
• enlarged breasts,
• amber or greenish discoloration of the urine,
• rectal bleeding or inflammation, or
• blood in the urine.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about flutamide (Eulexin)?

In rare cases, flutamide has caused severe liver damage resulting in death or hospitalization. Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, "flu-like" symptoms, yellow skin or eyes, itching, clay-colored stools, or dark urine. These symptoms may be early signs of liver damage.

Your doctor will need to monitor your liver function with blood tests before starting treatment with flutamide, every month for the first 4 months of treatment, and periodically thereafter.

Do not stop taking this medication without first talking to your doctor.

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