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Medications and Drugs

Brand Names: Lopid

Generic Name: gemfibrozil (Pronunciation: jem FYE broe zil)

What is gemfibrozil (Lopid)?

Gemfibrozil helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).

Gemfibrozil is used to treat very high cholesterol and triglyceride levels in people with pancreatitis.

Gemfibrozil is also used to lower the risk of stroke, heart attack, or other heart complications in people with high cholesterol and triglycerides who have not been helped by other treatment methods.

Gemfibrozil may also be used for purposes not listed in this medication guide.

Gemfibrozil 600 mg-APO

oval, white, imprinted with APO 034, 600

Gemfibrozil 600 mg-TEV

oval, white, imprinted with 93 670

Gemfibrozil 600 mg-WAT

oval, orange, imprinted with 454, WATSON

Gemfibrozil 600 mg-WC

elliptical, white, imprinted with WC, 084

Lopid 600 mg

elliptical, white, imprinted with Lopid, P-D 737

What are the possible side effects of gemfibrozil (Lopid)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • sharp pain in your upper stomach (especially after eating);
  • jaundice (yellowing of your skin or eyes);
  • blurred vision, eye pain, or seeing halos around lights;
  • pain or burning when you urinate;
  • unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine; or
  • pale skin, easy bruising, unusual bleeding, feeling light-headed or short of breath, rapid heart rate, trouble concentrating, purple or red pinpoint spots under your skin.

Less serious side effects may include:

  • upset stomach;
  • mild stomach pain, nausea, vomiting, diarrhea;
  • headache, dizziness, drowsiness;
  • mild joint or muscle pain;
  • loss of interest in sex, impotence, difficulty having an orgasm;
  • numbness or tingly feeling; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about gemfibrozil (Lopid)?

You should not use this medication if you are allergic to gemfibrozil, if you are also taking repaglinide (Prandin), or if you have gallbladder disease, liver disease, or severe kidney disease.

Call your doctor at once if you have a serious side effect such as sharp pain in your upper stomach (especially after eating), jaundice (yellowing of your skin or eyes), blurred vision, eye pain, or seeing halos around lights, or pain or burning when you urinate.

Avoid eating foods that are high in fat or cholesterol. Gemfibrozil will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Avoid drinking alcohol. It may interfere with your treatment.

To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Your liver and kidney function may also need to be tested. Visit your doctor regularly.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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