IN THIS ARTICLE
- What is glipizide (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
- What are the possible side effects of glipizide (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
- What is the most important information I should know about glipizide (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
- What should I discuss with my doctor before taking glipizide (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
- How should I take glipizide (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
- What happens if I miss a dose (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
- What happens if I overdose (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
- What should I avoid while taking glipizide (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
- What other drugs will affect glipizide (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
- Where can I get more information?
What happens if I miss a dose (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
Take the missed dose 30 minutes before your next meal, then return to your regular schedule. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Use glipizide regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
What happens if I overdose (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A glipizide overdose can cause life-threatening hypoglycemia.
Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).
What should I avoid while taking glipizide (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.
What other drugs will affect glipizide (GlipiZIDE XL, Glucotrol, Glucotrol XL)?
You may be more likely to have hyperglycemia (high blood sugar) if you are taking glipizide with other drugs that raise blood sugar, such as:
- diuretics (water pills);
- steroids (prednisone and others);
- phenothiazines (Compazine and others);
- thyroid medicine (Synthroid and others);
- birth control pills and other hormones;
- seizure medicines (Dilantin and others);
- niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);
- diet pills, medicines to treat asthma, colds or allergies; and
- heart or blood pressure medication such as diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others.
You may be more likely to have hypoglycemia (low blood sugar) if you are taking glipizide with other drugs that lower blood sugar, such as:
- nonsteroidal anti-inflammatory drugs (NSAIDs);
- aspirin or other salicylates (including Pepto-Bismol);
- sulfa drugs (Bactrim and others);
- a monoamine oxidase inhibitor (MAOI);
- beta-blockers (Tenormin and others);
- exenatide (Byetta);
- fluconazole (Diflucan);
- probenecid (Benemid);
- a blood thinner (warfarin, Coumadin, Jantoven, and others); and
- other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).
These lists are not complete and there are many other medicines that can increase or decrease the effects of glipizide on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about glipizide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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