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Medications and Drugs

Brand Names: Cuvposa, Robinul, Robinul Forte

Generic Name: glycopyrrolate (Pronunciation: glye koe PIE roe late)

What is glycopyrrolate (Cuvposa, Robinul, Robinul Forte)?

Glycopyrrolate reduces the secretions of certain organs in the body.

Glycopyrrolate helps to control conditions such as peptic ulcers that involve excessive stomach acid production.

Glycopyrrolate is also used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy.

Glycopyrrolate may also be used for purposes not listed in this medication guide.

Robinul 1 mg

round, white, imprinted with HPC 200

Robinul 2 mg

round, white, imprinted with HORIZON 205

What are the possible side effects of glycopyrrolate (Cuvposa, Robinul, Robinul Forte)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using glycopyrrolate and call your doctor at once if you have a serious side effect such as:

  • severe constipation, severe stomach pain and bloating;
  • diarrhea (especially if you have a colostomy or ileostomy);
  • feeling like you might pass out;
  • feeling very thirsty or hot, being unable to urinate, heavy sweating, weak pulse, or hot and dry skin; or
  • dry diapers, fussiness, or excessive crying in a child taking glycopyrrolate.

Less serious side effects may include:

  • dry mouth;
  • vomiting;
  • mild constipation;
  • stuffy nose, sinus pain; or
  • flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about glycopyrrolate (Cuvposa, Robinul, Robinul Forte)?

You should not use glycopyrrolate if you are allergic to it, or if you have bladder obstruction or other urination problems, a bowel obstruction called paralytic ileus, a blockage in your stomach or intestines, severe constipation, severe ulcerative colitis or toxic megacolon, glaucoma, myasthenia gravis, or if you also take potassium chloride.

Before you take glycopyrrolate, tell your doctor if you have kidney disease, heart disease, a heart rhythm disorder, a stomach disorder, a colostomy or ileostomy, a thyroid disorder, high blood pressure, vision problems, or numbness and tingling.

Take glycopyrrolate on an empty stomach, at least 1 hour before or 2 hours after a meal.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Drinking alcohol can increase certain side effects of glycopyrrolate, such as dizziness and drowsiness.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Glycopyrrolate can decrease sweating and you may be more prone to heat stroke.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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