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Brand Names: Levall 5.0, Tussafed-HC, Tussafed-HCG

Generic Name: guaifenesin, hydrocodone, and phenylephrine (Pronunciation: gwye FEH neh sin , high droe KOE dohn , and feh nill EH frin)

• What is guaifenesin, hydrocodone, and phenylephrine (Levall 5.0, Tussafed-HC, Tussafed-HCG)?
• What are the possible side effects of guaifenesin, hydrocodone, and phenylephrine (Levall 5.0, Tussafed-HC, Tussafed-HCG)?
• What is the most important information I should know about guaifenesin, hydrocodone, and phenylephrine (Levall 5.0, Tussafed-HC, Tussafed-HCG)?
• What should I discuss with my healthcare provider before taking guaifenesin, hydrocodone, and phenylephrine (Levall 5.0, Tussafed-HC, Tussafed-HCG)?
• How should I take guaifenesin, hydrocodone, and phenylephrine (Levall 5.0, Tussafed-HC, Tussafed-HCG)?
• What happens if I miss a dose (Levall 5.0, Tussafed-HC, Tussafed-HCG)?
• What happens if I overdose (Levall 5.0, Tussafed-HC, Tussafed-HCG)?
• What should I avoid while taking guaifenesin, hydrocodone, and phenylephrine (Levall 5.0, Tussafed-HC, Tussafed-HCG)?
• What other drugs will affect guaifenesin, hydrocodone, and phenylephrine (Levall 5.0, Tussafed-HC, Tussafed-HCG)?
• Where can I get more information?

What is guaifenesin, hydrocodone, and phenylephrine (Levall 5.0, Tussafed-HC, Tussafed-HCG)?

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Hydrocodone is a narcotic. It is a pain reliever and a cough suppressant.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of guaifenesin, hydrocodone, and phenylephrine is used to treat cough and nasal congestion, and to reduce chest congestion caused by the common cold, infections, or allergies.

Guaifenesin, hydrocodone, and phenylephrine may also be used for other purposes not listed in this medication guide.

What are the possible side effects of guaifenesin, hydrocodone, and phenylephrine (Levall 5.0, Tussafed-HC, Tussafed-HCG)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking this medication and call your doctor at once if you have any of these serious side effects:

• fast, pounding, or uneven heartbeat;
• severe dizziness, anxiety, restless feeling, or nervousness;
• easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
• increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure).
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

Less serious side effects may include:

• dizziness or headache;
• feeling excited or restless;
• sleep problems (insomnia);
• nausea, vomiting, or stomach upset;
• mild loss of appetite;
• warmth, tingling, or redness under your skin; or
• skin rash or itching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about guaifenesin, hydrocodone, and phenylephrine (Levall 5.0, Tussafed-HC, Tussafed-HCG)?

Hydrocodone may be habit-forming and should be used only by the person this medicine was prescribed for. Keep the medication in a secure place where others cannot get to it.

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Do not use any other over-the-counter cold, allergy, or cough medicine without first asking your doctor or pharmacist. Guaifenesin and phenylephrine are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug.

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