1. Heart Disease (Coronary Artery Disease) Slideshow Pictures
2. Slideshow: Atrial Fibrillation Causes, Tests, and Treatment
3. Take the Heart Disease Quiz!

What happens if I miss a dose (BiDil)?

Take the missed dose as soon as you remember. If your next regularly scheduled dose is within 2 hours, skip the dose you missed and take only the next dose. Do Not take a double dose of this medication.

What happens if I overdose (BiDil)?

Seek emergency medical attention.

Symptoms of an hydralazine and isosorbide dinitrate overdose include a severe throbbing headache, difficult or slow breathing, muscle cramps, nausea, vomiting, diarrhea, fever, dizziness, fainting, an irregular or slow heart beat, changes in vision, confusion, flushing, and seizures.

What should I avoid while taking hydralazine and isosorbide dinitrate (BiDil)?

Use caution when driving, operating machinery, or performing other hazardous activities. Hydralazine and isosorbide dinitrate may cause dizziness. If you experience dizziness, avoid these activities. Also, stand up slowly from a lying or sitting position.

Avoid alcohol. Alcohol also widens your blood vessels, and it can cause very low blood pressure, dizziness, and drowsiness. If you consume alcohol, you could endanger yourself or others.

Do not stop taking hydralazine and isosorbide dinitrate suddenly. Talk to your doctor before you stop taking the drug completely.

What other drugs will affect hydralazine and isosorbide dinitrate (BiDil)?

Before taking hydralazine and isosorbide dinitrate, tell your doctor if you are taking any of the following medicines:

• dihydroergotamine (D.H.E. 45); or
• any other heart medicines, especially those used to treat high blood pressure or irregular heartbeats.

You may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with hydralazine and isosorbide dinitrate or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

Your pharmacist has additional information about hydralazine and isosorbide dinitrate written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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