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What should I discuss with my doctor before taking hydrochlorothiazide and hydralazine (Hydra-Zide)?

You should not use this medication if you are allergic to hydralazine (Apresoline) or hydrochlorothiazide, or if you have:

• coronary artery disease;
• rheumatic heart disease affecting the mitral valve; or
• if you are unable to urinate.

To make sure you can safely take hydrochlorothiazide and hydralazine, tell your doctor if you have any of these other conditions:

• kidney disease;
• liver disease;
• glaucoma;
• angina pectoris (chest pain);
• asthma or allergies;
• gout;
• lupus;
• diabetes;
• an allergy to sulfa drugs or penicillin; or
• if you have ever had stroke.

FDA pregnancy category C. It is not known whether hydrochlorothiazide and hydralazine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether hydrochlorothiazide and hydralazine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using hydrochlorothiazide and hydralazine.

How should I take hydrochlorothiazide and hydralazine (Hydra-Zide)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low salt diet, or taking diuretics (water pills). Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Your blood pressure will need to be checked often. Your blood and urine may both be tested if you have been vomiting or are dehydrated. Visit your doctor regularly.

Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using a thiazide diuretic.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture, heat, and light.

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