Medications and Drugs

1. High Blood Pressure (Hypertension) Slideshow Pictures
2. Take the Salt Quiz!
3. Lowering Blood Pressure Exercise Tips Slideshow Pictures

Brand Names: Inderide

Generic Name: hydrochlorothiazide and propranolol (Pronunciation: HYE droe klor oh THYE a zide and proe PRAN oh lol)

• What is hydrochlorothiazide and propranolol (Inderide)?
• What are the possible side effects of hydrochlorothiazide and propranolol (Inderide)?
• What is the most important information I should know about hydrochlorothiazide and propranolol (Inderide)?
• What should I discuss with my doctor before taking hydrochlorothiazide and propranolol (Inderide)?
• How should I take hydrochlorothiazide and propranolol (Inderide)?
• What happens if I miss a dose (Inderide)?
• What happens if I overdose (Inderide)?
• What should I avoid while taking hydrochlorothiazide and propranolol (Inderide)?
• What other drugs will affect hydrochlorothiazide and propranolol (Inderide)?
• Where can I get more information?

What is hydrochlorothiazide and propranolol (Inderide)?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Propranolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

The combination of hydrochlorothiazide and propranolol is used to treat high blood pressure (hypertension).

Hydrochlorothiazide and propranolol may also be used for purposes not listed in this medication guide.

HCTZ-Propranolol 40 mg-25 mg-MYL

round, white, imprinted with MYLAN 731

HCTZ-Propranolol 80 mg-25 mg-MYL

round, white, imprinted with MYLAN 347

What are the possible side effects of hydrochlorothiazide and propranolol (Inderide)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

• eye pain, vision problems;
• swelling, rapid weight gain, feeling short of breath, even with mild exertion;
• fast, slow, or uneven heartbeat;
• easy bruising or bleeding;
• numbness or tingly feeling in your hands or feet;
• feeling weak, drowsy, restless, or light-headed;
• nausea, vomiting, dry mouth, extreme thirst, headache, confusion, hallucinations, seizure (convulsions);
• increased urination, leg discomfort, muscle pain or weakness or limp feeling;
• urinating less than usual or not at all;
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
• upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

• diarrhea, constipation, upset stomach;
• dizziness, spinning sensation;
• sore throat, body aches;
• blurred vision;
• depressed mood; or
• sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about hydrochlorothiazide and propranolol (Inderide)?

You should not use this medication if you have asthma, severe or uncontrolled heart failure, a heart condition called "sick sinus syndrome" or "AV block," or if you are unable to urinate.

Before using this medication, tell your doctor if you have congestive heart failure, kidney or liver disease, cirrhosis, glaucoma, bronchospastic lung disease, gout, lupus, diabetes, a thyroid disorder, or if you are allergic to sulfa drugs or penicillin.

If you are diabetic, check your blood sugar carefully. Using propranolol can make it harder for you to tell when you have low blood sugar. Your insulin or diabetic medication needs may change while you are taking hydrochlorothiazide and propranolol. Talk with your doctor before changing any doses.

Drinking alcohol can further lower your blood pressure and may increase your blood levels of propranolol.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Keep using this medication even if you feel fine. High blood pressure often has no symptoms.

There are many other medicines that can interact with hydrochlorothiazide and propranolol. Tell your doctor about all the prescription and over-the-counter medications you use.

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