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What should I discuss with my doctor before taking hydrochlorothiazide and spironolactone (Aldactazide)?

You should not use this medication if you are allergic to hydrochlorothiazide or spironolactone, or if you have:

• kidney disease or are unable to urinate;
• high potassium levels (hyperkalemia); or
• if you are taking potassium supplements.

To make sure you can safely take hydrochlorothiazide and spironolactone, tell your doctor if you have any of these other conditions:

• diabetes;
• heart disease;
• cirrhosis or other liver disease;
• glaucoma;
• a breathing disorder;
• gout;
• lupus;
• an allergy to sulfa drugs or penicillin;
• a pancreas disorder; or
• if you are using another blood pressure medication or a steroid.

FDA pregnancy category C. It is not known whether hydrochlorothiazide and spironolactone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Hydrochlorothiazide passes into breast milk and could cause harm to a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take hydrochlorothiazide and spironolactone (Aldactazide)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Take each dose with a full glass of water.

To be sure this medication is not causing harmful effects, your blood will need to be tested often. Your kidney or liver function may also need to be tested. Visit your doctor regularly.

Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using a thiazide diuretic.

If you need surgery, tell the surgeon ahead of time that you are using hydrochlorothiazide and spironolactone. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

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