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Medications and Drugs

Brand Names: Dilaudid

Generic Name: hydromorphone (rectal) (Pronunciation: hye dro MOR fone)

What is hydromorphone rectal (Dilaudid)?

Hydromorphone is in a group of drugs called narcotic pain relievers. It is similar to morphine.

Hydromorphone rectal is used to treat moderate to severe pain.

Hydromorphone rectal may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of hydromorphone rectal (Dilaudid)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • shallow breathing, slow heartbeat;
  • seizure (convulsions);
  • cold, clammy skin;
  • confusion;
  • severe weakness or dizziness; or
  • feeling light-headed, fainting.

Less serious side effects are more likely to occur, such as:

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about hydromorphone rectal (Dilaudid)?

Do not use hydromorphone with alcohol, other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.

You may have withdrawal symptoms when you stop using this medication after using it over a long period of time. Do not stop using hydromorphone suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

Hydromorphone may be habit-forming and should be used only by the person it was prescribed for. Hydromorphone should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Hydromorphone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Never use more hydromorphone than is prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Do not take hydromorphone rectal by mouth. It is for use only in your rectum.

This medication comes with patient instructions for using the rectal suppository. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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