What happens if I miss a dose (Makena, Prodrox)?
Call your doctor for instructions if you miss an appointment for your hydroxyprogesterone injection.
What happens if I overdose (Makena, Prodrox)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while receiving hydroxyprogesterone (Makena, Prodrox)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What other drugs will affect hydroxyprogesterone (Makena, Prodrox)?
Tell your doctor about all other medicines you use, especially:
- acetaminophen (Tylenol);
- alosetron (Lotronex);
- betaxolol (Kerlone) or propranolol (Inderal, InnoPran);
- cyclophosphamide (Gengraf, Neoral, Sandimmune);
- efavirenz (Sustiva, Atripla);
- methadone (Methadose, Diskets, Dolophine);
- mexiletine (Mexitil);
- nicotine (Nicorette, Commit, Habitrol, Nicotrol, Nicoderm);
- rifabutin (Mycobutin) or rifampin (Rifater, Rifadin, Rifamate);
- riluzole (Rilutek);
- ropinirole (Requip);
- selegiline (Eldepryl, Emsam, Zelapar);
- tacrine (Cognex);
- an antidepressant such as bupropion (Wellbutrin), clomipramine (Anafranil), doxepin (Adapin, Sinequan), duloxetine (Cymbalta), fluvoxamine (Luvox), or mirtazepine (Remeron),
- asthma medication such as aminophylline (Phyllocontin, Truphylline) or theophylline (Elixophyllin, Theo-24, Theochron, Uniphyl);
- cancer medicine such as dacarbazine (DTIC-Dome), flutamide (Eulexin), or irinotecan (Camptosar);
- medicines to treat psychiatric disorders, such as clozapine (Clozaril, FazaClo), pimozide (Orap), promethazine (Phenergan), thiothixene (Navane), or trifluoperazine (Stelazine); or
- a muscle relaxer such as cyclobenzaprine (Flexeril) or tizanidine (Zanaflex).
This list is not complete and other drugs may interact with hydroxyprogesterone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your doctor or pharmacist can provide more information about hydroxyprogesterone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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