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Medications and Drugs

Brand Names: Darcalma, Darpaz, Hyophen, Phosphasal, Prosed/DS, Urelle, Uribel, Uro Blue, Urogesic Blue (obsolete), Ustell, Uta, UTICAP, Utira, Utrona-C

Generic Name: hyoscyamine, methenamine, methylene blue, and phenyl salicylate (Pronunciation: HYE oh SYE a meen, meth EN a meen, METH il een BLUE, FEEN il sa LIS il ate)

What is hyoscyamine, methenamine, methylene blue, and phenyl salicylate (Darcalma, Darpaz, Hyophen, Phosphasal, Prosed/DS, Urelle, Uribel, Uro Blue, Urogesic Blue (obsolete), Ustell, Uta, UTICAP, Utira, Utrona-C)?

Hyoscyamine produces many effects in the body, including relief from muscle spasms.

Methenamine and methylene blue work as mild antiseptics that fight bacteria in the urine and bladder.

Phenyl salicylate is a mild pain reliever.

The combination of hyoscyamine, methenamine, methylene blue, and phenyl salicylate is used to treat bladder irritation (pain, burning inflammation) caused by urinary tract infection. This medication is also used to prevent bladder discomfort during a medical procedure.

Hyoscyamine, methenamine, methylene blue, and phenyl salicylate may also be used for purposes not listed in this medication guide.

Urelle

round, blue, imprinted with P-002

What are the possible side effects of hyoscyamine, methenamine, methylene blue, and phenyl salicylate?

Methylene blue will most likely cause your urine or stools to appear blue or green in color. This is a normal side effect of the medication and will not cause any harm.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using hyoscyamine, methenamine, methylene blue, and phenyl salicylate and call your doctor at once if you have a serious side effect such as:

  • severe dizziness, blurred vision, fast heart rate;
  • agitation, confusion, feeling restless or excited;
  • painful or difficult urination; or
  • feeling short of breath.

Less serious side effects may include:

  • mild dizziness;
  • drowsiness; or
  • flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about hyoscyamine, methenamine, methylene blue, and phenyl salicylate?

You should not use hyoscyamine, methenamine, methylene blue, and phenyl salicylate if you are allergic to it.

Before taking this medication, tell your doctor if you have any type of heart problem (congestive heart failure, coronary heart disease, a heart rhythm or heart valve disorder), glaucoma, an enlarged prostate, bladder obstruction, myasthenia gravis, a stomach ulcer or obstruction, or if you are allergic to belladonna (Donnatal and others).

Drink plenty of liquids while you are taking this medication.

If you have an eye exam and your pupils are dilated with eye drops, tell the eye doctor ahead of time that you are using hyoscyamine, methenamine, methylene blue, and phenyl salicylate.

Many drugs can interact with this medicine. Also, hyoscyamine can make it harder for your body to absorb other medications you take by mouth. Tell your doctor about all other medicines you use.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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