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What happens if I miss a dose (In-111 Zevalin, Y-90 Zevalin)?

Contact your doctor if you miss an appointment for your ibritumomab injection.

What happens if I overdose (In-111 Zevalin, Y-90 Zevalin)?

Seek emergency medical attention if you think you have received too much of this medicine.

Overdose symptoms may include weakness, pale skin, and easy bruising or bleeding.

What should I avoid while using ibritumomab (In-111 Zevalin, Y-90 Zevalin)?

Avoid contact with people who have colds, the flu, or other contagious illnesses. Contact your doctor immediately if you develop signs of infection.

Do not receive a "live" vaccine while you are being treated with ibritumomab, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you.

What other drugs will affect ibritumomab (In-111 Zevalin, Y-90 Zevalin)?

Before receiving ibritumomab, tell your doctor if you are using any type of blood thinner or medication use to prevent blood clots, such as:

• warfarin (Coumadin);
• alteplase (Activase);
• anistreplase (Eminase);
• clopidogrel (Plavix);
• dipyridamole (Persantine);
• streptokinase (Kabikinase, Streptase);
• sulfinpyrazone (Anturane);
• ticlopidine (Ticlid); or
• urokinase (Abbokinase).

This list is not complete and there may be other drugs that can interact with ibritumomab. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist can provide more information about ibritumomab.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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