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ibuprofen and pseudoephedrine (cont.)

IN THIS ARTICLE

What should I discuss with my doctor before taking ibuprofen and pseudoephedrine (Advil Cold & Sinus, Advil Cold and Sinus Liqui-Gel, Children's Ibuprofen Cold Relief, Dristan Sinus, Motrin Childrens Cold)?

Do not use this medication just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Ibuprofen may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.

Ibuprofen may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking ibuprofen, especially in older adults.

Do not use ibuprofen and pseudoephedrine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

You should not use this medication if you are allergic to ibuprofen or pseudoephedrine, or if you have:

  • a stomach ulcer or active bleeding in your stomach or intestines;
  • polyps in your nose; or
  • a history of allergic reaction to aspirin or other NSAIDs.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

Taking ibuprofen during the last 3 months of pregnancy may result in birth defects and prolonged labor and delivery. Do not take this medication without medical advice if you are pregnant.

It is not known whether ibuprofen and pseudoephedrine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take ibuprofen and pseudoephedrine (Advil Cold & Sinus, Advil Cold and Sinus Liqui-Gel, Children's Ibuprofen Cold Relief, Dristan Sinus, Motrin Childrens Cold)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

An overdose of ibuprofen can damage your stomach or intestines. Adults should not take more than 800 milligrams per dose or 3200 mg per day (4 maximum doses).

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Call your doctor if you have a fever lasting longer than 3 days, if you have new symptoms, or if your condition does not improve after taking this medication for 7 days.

If you need surgery, tell the surgeon ahead of time that you are using ibuprofen and pseudoephedrine. You may need to stop using the medicine for a short time.

Store at room temperature away from moisture and heat.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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