Medications and Drugs
Brand Names: Tofranil, Tofranil-PM
Generic Name: imipramine (Pronunciation: im IP ra meen)
What is imipramine (Tofranil, Tofranil-PM)?
Imipramine is a tricyclic antidepressant. Imipramine affects chemicals in the brain that may become unbalanced.
Imipramine is used to treat symptoms of depression. Imipramine is sometimes used to treat bed-wetting in children ages 6 and older.
Imipramine may also be used for purposes not listed in this medication guide.
Imipramine 10 mg-GG
round, yellow, imprinted with GG, 41
Imipramine 10 mg-MUT
round, yellow, imprinted with MP 4
Imipramine 10 mg-PAR
triangular, yellow, imprinted with par, 54
Imipramine 25 mg-GG
round, beige, imprinted with 47, GG
Imipramine 25 mg-PAR
round, brown, imprinted with 55, par
Imipramine 25 mg-URL
round, brown, imprinted with MP 8
Imipramine 50 mg-GG
round, green, imprinted with GG, 42
Imipramine 50 mg-MUT
round, green, imprinted with MP 79
Imipramine 50 mg-PAR
round, green, imprinted with 56, par
Imipramine Pamoate 100 mg-ROX
capsule, red/yellow, imprinted with 54758
Imipramine Pamoate 125 mg-ROX
capsule, brown, imprinted with 54466
Imipramine Pamoate 150 mg-ROX
capsule, brown, imprinted with 54 161
Imipramine Pamoate 75 mg-ROX
capsule, brown, imprinted with 54591
Tofranil 25 mg-MAL
round, orange, imprinted with M inside a box, 25
Tofranil 50 mg-MAL
round, orange, imprinted with 50, M inside a box
Tofranil 10 mg-MAL
triangular, orange, imprinted with 10, M inside a box
What are the possible side effects of imipramine (Tofranil, Tofranil-PM)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have:
Other common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about imipramine (Tofranil, Tofranil-PM)?
You should not take this medicine if you have recently had a heart attack, or if you are allergic to imipramine or similar antidepressants such as amitriptyline, amoxapine, clomipramine, desipramine, doxepin, nortriptyline, protriptyline, or trimipramine.
Do not use imipramine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?