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Brand Names: Gamunex-C

Generic Name: immune globulin (intravenous and subcutaneous) (Pronunciation: im MYOON GLOB yoo lin)

• What is immune globulin (Gamunex-C)?
• What are the possible side effects of immune globulin (Gamunex-C)?
• What is the most important information I should know about immune globulin (Gamunex-C)?
• What should I discuss with my healthcare provider before taking immune globulin (Gamunex-C)?
• How should I use immune globulin (Gamunex-C)?
• What happens if I miss a dose (Gamunex-C)?
• What happens if I overdose (Gamunex-C)?
• What should I avoid while using immune globulin (Gamunex-C)?
• What other drugs will affect immune globulin (Gamunex-C)?
• Where can I get more information?

What is immune globulin (Gamunex-C)?

Immune globulin is a sterilized solution made from human plasma. It contains the antibodies to help your body protect itself against infection from various diseases.

Immune globulin intravenous and subcutaneous (for injection into a vein or under the skin) is used to treat primary immune deficiency, idiopathic thrombocytopenic purpura (ITP), or chronic inflammatory demyelinating polyneuropathy.

Immune globulin may also be used for purposes not listed in this medication guide.

What are the possible side effects of immune globulin (Gamunex-C)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; wheezing, difficulty breathing; dizziness, feeling like you might pass out; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• swelling, rapid weight gain, feeling short of breath, urinating less than usual or not at all;
• pain, swelling, redness, warmth, or a lump in your arms or legs;
• pale or yellowed skin, dark colored urine, fever, confusion or weakness;
• fever, chills, headache, neck stiffness, increased sensitivity to light, purple spots on the skin, and/or seizure (convulsions);
• chest pain or tightness, trouble breathing; or
• signs of new infection such as high fever, chills, body aches, flu symptoms, or sores in your mouth and throat.

Less serious side effects may include:

• headache, tired feeling;
• low fever, sore throat, cough;
• redness, itching, and swelling of skin where the injection was given;
• nausea, vomiting;
• back pain, joint pain, pain in your arms or legs; or
• mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about immune globulin (Gamunex-C)?

You should not use this medication if you have ever had an allergic reaction to an immune globulin, or if you have immune globulin A (IgA) deficiency with antibody to IgA.

Before using this medication, tell your doctor if you have kidney disease, heart disease, diabetes, hyperproteinemia (high levels of protein in the blood), paraproteinemia (abnormal proteins in the blood), a serious infection called sepsis, blood circulation problems or a blood vessel disorder, a history of stroke or blood clot, if you are on a low-salt diet, if you take diuretics, if you are 65 or older, or if you have been bed-ridden due to severe illness.

Immune globulin can harm your kidneys, and this effect is increased when you also use certain other medicines harmful to the kidneys. Before using immune globulin, tell your doctor about all other medications you use. Many other drugs (including some over-the-counter medicines) can be harmful to the kidneys.

You may need a dose adjustment if you are exposed to measles, or if you travel to an area where this disease is common.

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