What happens if I miss a dose (Crixivan)?
Take the missed dose as soon as you remember and take your next dose at the regularly scheduled time. If you are more than 2 hours late in taking your indinavir, skip the missed dose and take the next regularly scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Crixivan)?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an indinavir overdose may include nausea, vomiting, diarrhea, lower back pain, and blood in your urine.
What should I avoid while taking indinavir (Crixivan)?
If you also take didanosine, take it 1 hour before or after you take indinavir, on an empty stomach.
Taking indinavir will not prevent you from passing HIV to other people through unprotected sex or sharing of needles. Talk with your doctor about safe methods of preventing HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
What other drugs will affect indinavir (Crixivan)?
Before taking indinavir, tell your doctor if you are using:
- injectable midazolam (Versed);
- fluticasone (Advair, Flonase, Flovent);
- St. John's wort;
- antibiotics such as clarithromycin (Biaxin), itraconazole (Sporanox), ketoconazole (Nizoral), rifabutin (Mycobutin), or rifampin (Rifadin, Rimactane, Rifater);
- antidepressants such as trazodone (Desyrel), and others;
- a calcium channel blocker such as amlodipine (Caduet, Lotrel, Norvasc), diltiazem (Tiazac, Cartia, Dilacor), felodipine (Plendil), nifedipine (Procardia, Adalat), or verapamil (Calan, Covera, Isoptin, Verelan);
- cholesterol-lowering medicine such as atorvastatin (Lipitor), lovastatin (Mevacor, Altocor), rosuvastatin (Crestor), or simvastatin (Zocor);
- drugs that weaken the immune system, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf);
- heart rhythm medications such as quinidine (Quinaglute, Quinidex);
- insulin or diabetes medication you take by mouth;
- medicines to treat erectile dysfunction, such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra);
- other HIV /AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva), lopinavir/ritonavir (Kaletra), or ritonavir (Norvir); or
- seizure medications such as carbamazepine (Carbatrol, Tegretol), phenobarbital (Luminal, Solfoton), or phenytoin (Dilantin).
This list is not complete and there are many other medicines that can interact with indinavir. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about indinavir.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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