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What should I discuss with my health care provider before receiving iodixanol (Visipaque)?

Tell your doctor if you have ever had any type of reaction to another contrast agent.

Iodixanol should not be given to a child who has recently used a laxative (stool softener) or has not eaten properly before the test. You should not receive iodixanol if you have any type of active infection.

Before receiving iodixanol, tell your doctor if you have:

• a brain tumor or hematoma;
• a recent head or brain injury;
• epilepsy or other seizure disorder;
• kidney disease;
• liver disease;
• heart disease, including congestive heart failure;
• sickle cell anemia;
• a history of stroke, blood clots, or circulation problems;
• asthma, hay fever, or a history of food or drug allergies;
• diabetes;
• a weak immune system caused by disease or by taking certain medicines such as steroids or cancer treatment;
• an autoimmune disorder such as lupus, multiple sclerosis, or rheumatoid arthritis;
• multiple myeloma (bone cancer);
• pheochromocytoma;
• a thyroid disorder.

If you have any of these conditions, you may not be able to receive iodixanol, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether iodixanol passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may need special care in avoiding dehydration by drinking extra fluids before and after the radiologic test. Your kidney function may also need to be watched closely after you have received iodixanol.

How is iodixanol used (Visipaque)?

Iodixanol is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting, just before your radiologic test.

Drink extra fluids before and after you receive iodixanol. This medication can cause you to get dehydrated, which can lead to dangerous effects on your kidneys. Follow your doctor's instructions about the types and amount of fluids you should drink before and after your test.

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