isosorbide mononitrate (cont.)
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What should I discuss with my healthcare provider before taking isosorbide mononitrate (Imdur, ISMO, Monoket)?
Do not use isosorbide mononitrate if you are taking sildenafil (Viagra, Revatio). A dangerous drug interaction could occur, leading to serious side effects.
You should not use this medication if you are allergic to isosorbide mononitrate, isosorbide dinitrate, (Isordil, Dilatrate, Isochron), or nitroglycerin, or if you have early signs of a heart attack (chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling).
To make sure you can safely take isosorbide mononitrate, tell your doctor if you have any of these other conditions:
FDA pregnancy category C. It is not known whether isosorbide mononitrate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether isosorbide mononitrate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Isosorbide mononitrate can cause severe headaches, especially when you first start using it. These headaches may gradually become less severe as you continue to use isosorbide mononitrate. Do not stop taking the medication. Ask your doctor before using any headache pain medication.
How should I take isosorbide mononitrate (Imdur, ISMO, Monoket)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results.
Not all brands and forms of isosorbide mononitrate are taken the same number of times per day. You may need to take the medication only once daily, in the morning after getting out of bed. Or you may need a second dose later in the day. Follow your doctor's dosing instructions very carefully.
If possible, try to rest or stay seated when you use this medication. Isosorbide mononitrate can cause dizziness or fainting.
Take this medication with at least 4 ounces of water or other liquid.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. Breaking the pill may cause too much of the drug to be released at one time.
This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using isosorbide mononitrate.
Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low salt diet, or taking diuretics (water pills). Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.
Use isosorbide mononitrate regularly to prevent an angina attack. Get your prescription refilled before you run out of medicine completely.
Do not stop taking isosorbide mononitrate suddenly. Stopping suddenly could cause a severe angina attack.
Do not change brands of isosorbide mononitrate without the approval of your doctor.
Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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