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What should I discuss with my health care provider before taking l-methylfolate (Deplin, Zervalx)?

You should not use this medication if you have ever had an allergic reaction to l-methylfolate.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before using l-methylfolate, tell your doctor if you have:

• a history of bipolar disorder (manic depression);
• vitamin B12 deficiency; or
• pernicious anemia.

Zervalx may be used throughout pregnancy or while you are trying to get pregnant.

Before you take Deplin, tell your doctor if you are pregnant or breast-feeding.

How should I take l-methylfolate (Deplin, Zervalx)?

Do not use l-methylfolate without the advice of a doctor. Never share this medication with another person, even if you believe they have the same condition you have.

Use this product exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Use only the brand and strength of l-methylfolate that your doctor has prescribed. Do not switch brands without your doctor's advice.

You may take l-methylfolate with or without food. Follow your doctor's instructions.

L-methylfolate is only part of a complete program of treatment that may also include other medications, and psychological counseling when used in people with depression or schizophrenia. Follow your medication and counseling routines very closely.

Store l-methylfolate at room temperature away from moisture, heat, and light.

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