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What should I discuss with my healthcare provider before taking laureth-9 (Asclera)?

You should not receive this medication if you are allergic to laureth-9, lauromacrogol 400, or polidocanol, or if you have:

• a blood clot disorder such as deep vein thrombosis (DVT) or thrombophlebitis (swelling of a vein caused by a blood clot); or
• Buerger's disease (a blood clotting disorder affecting the arms and legs).

To make sure you can safely receive laureth-9, tell your doctor about all of your medical conditions or allergies.

FDA pregnancy category C. It is not known whether laureth-9 will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while receiving this medication..

It is not known whether laureth-9 passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using laureth-9.

How is laureth-9 given (Asclera)?

Laureth-9 is injected with a small needle directly into a varicose or spider vein. You will receive this injection in a clinic or hospital setting.

The number of injections you receive will depend on the number of spider or varicose veins being treated.

Laureth-9 must be injected slowly into the vein. Your caregivers will apply slight pressure to the vein during an injection.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when laureth-9 is injected. You will be watched closely after your injection, to make sure this medication is not causing harmful effects.

After the needle is removed from the vein, a compression bandage or stocking will be placed on the leg to prevent blood clots from forming.

When your treatment session is finished, your caregivers may want you to walk around for 15 or 20 minutes. Your doctor may instruct you to take daily walks for a few days after your treatment with laureth-9.

You may need to wear compression stockings for several days or weeks after your treatment. Carefully follow your doctor's instructions about caring for yourself after receiving this medication.

You may need additional treatment sessions with laureth-9 to best treat the varicose vein. At least 1 week should pass between treatment sessions.

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