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Medications and Drugs

Brand Names: Femara

Generic Name: letrozole (Pronunciation: LET roe zol)

What is letrozole (Femara)?

Letrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

Letrozole is used to treat breast cancer in postmenopausal women. It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years.

Letrozole may also be used for purposes not listed in this medication guide.

Letrozole 2.5 mg-TEV

round, yellow, imprinted with TEVA, B1

What are the possible side effects of letrozole (Femara)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

  • dizziness, drowsiness, weakness, tired feeling;
  • hot flashes, warmth in your face or chest;
  • flushing (warmth, redness, or tingly feeling);
  • headache;
  • nausea, constipation;
  • bone pain, muscle or joint pain;
  • numbness, tingling, weakness, or stiffness in your hand or fingers;
  • pain in your hand that spreads to your arm, wrist, forearm, or shoulder;
  • night sweats; or
  • weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about letrozole (Femara)?

Letrozole can harm an unborn baby or cause birth defects. Do not use if you are pregnant.

You should not use this medication if you are allergic to letrozole, or if you have not gone completely through menopause.

Before taking letrozole, tell your doctor if you have osteoporosis, high cholesterol, or liver disease (especially cirrhosis).

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

To be sure letrozole is helping your condition, your blood may need to be tested often. Your bone mineral density may also need to be checked. Visit your doctor regularly.

Tell your doctor about all other medicines you use, especially tamoxifen (Soltamox).



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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