Medications and Drugs
Generic Name: leucovorin (oral) (Pronunciation: loo koe VOR in)
What is leucovorin ()?
Leucovorin is a form of folic acid. Folic acid helps your body produce and maintain new cells, and also helps prevent changes to DNA that may lead to cancer. Folic acid is present in many foods such as dried beans, peas, oranges, spinach, and others.
Leucovorin is used to reduce the side effects of large doses or accidental overdose of medications that can reduce the effects of folic acid in the body. This includes methotrexate (Rheumatrex), pyrimethamine (Daraprim), trimethoprim (Trimpex, Proloprim), and others.
Leucovorin may also be used for purposes other than those listed in this medication guide.
Leucovorin 10 mg-ROX
round, white, imprinted with 54 942
Leucovorin 15 mg-ROX
round, yellow, imprinted with 54 650
Leucovorin 25 mg-BAR
round, green, imprinted with b, 485
Leucovorin 25 mg-ROX
round, yellow, imprinted with 54 013
Leucovorin 5 mg-BAR
round, white, imprinted with b, 484
Leucovorin 5 mg-ROX
round, white, imprinted with 54 293
What are the possible side effects of leucovorin ()?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about leucovorin ()?
Do not take leucovorin if you have anemia that is caused by a lack of vitamin B12.
Before taking leucovorin, tell your doctor if you are allergic to any drugs, or if you have kidney, liver, or lung disease.
Before taking leucovorin, tell your doctor if you are using fluorouracil (Adrucil), phenytoin (Dilantin), fosphenytoin (Cerebyx), ethotoin (Peganone), phenobarbital (Luminal, Solfoton), or primidone (Mysoline).
When treating an accidental overdose, leucovorin should be started as soon as possible for best effect.
To be sure this medication is helping your condition, your blood will need to be tested often. This will help your doctor determine how long to treat you with leucovorin.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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