Medications and Drugs
Brand Names: Eligard, Lupron, Lupron Depot, Lupron Depot-Ped
Generic Name: leuprolide (Pronunciation: LOO proe lide)
What is leuprolide (Eligard, Lupron, Lupron Depot, Lupron Depot-Ped)?
Leuprolide is a man-made form of a hormone that regulates many processes in the body. Leuprolide overstimulates the body's own production of certain hormones, which causes that production to shut down temporarily. Leuprolide reduces the amount of testosterone in men or estrogen in women.
Leuprolide is used in men to treat the symptoms of prostate cancer. Leuprolide treats only the symptoms of prostate cancer and does not treat the cancer itself. Use any other medications your doctor has prescribed to best treat your condition.
Leuprolide is also used to treat precocious (early-onset) puberty in both male and female children.
Leuprolide may also be used for purposes not listed in this medication guide.
What are the possible side effects of leuprolide (Eligard, Lupron, Lupron Depot, Lupron Depot-Ped)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Rare but serious side effects may include:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about leuprolide (Eligard, Lupron, Lupron Depot, Lupron Depot-Ped)?
Leuprolide can harm an unborn baby or cause birth defects. Do not use if you are pregnant.
You should not breast-feed while you are using leuprolide.
You should not use this medication if you are allergic to leuprolide or similar medications such as buserelin (Suprefact, Suprecor), goserelin (Zoladex), histrelin (Supprelin, Vantas), or nafarelin (Synarel).
You should not use leuprolide if you have abnormal vaginal bleeding that has not been diagnosed by a doctor.
Before using leuprolide, tell your doctor if you have epilepsy, asthma, migraines, heart or kidney disease, a history of depression, osteoporosis, bone cancer affecting your spine, blood in your urine, or if you are unable to urinate.
Tell your doctor if you have a personal or family history of osteoporosis, or if you have any risk factors for bone loss such as smoking, alcohol use, or taking steroid or seizure medications long term. Long-term use of this medication may decrease bone density, possibly leading to osteoporosis.
Certain brands or strengths of leuprolide are used to treat only men and should not be used in women or children. Always check your medication to make sure you have received the correct brand and strength prescribed by your doctor.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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