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What should I discuss with my healthcare provider before using leuprolide (Eligard, Lupron, Lupron Depot, Lupron Depot-Gyn, Lupron Depot-Ped)?
Certain brands or strengths of leuprolide are used to treat only men and should not be used in women or children. Always check your medication to make sure you have received the correct brand and strength prescribed by your doctor. Ask the pharmacist if you have any questions about the medicine you receive at the pharmacy.
You should not use this medication if you are allergic to leuprolide or similar medications such as buserelin (Suprefact, Suprecor), goserelin (Zoladex), histrelin (Supprelin), nafarelin (Synarel), or if you have:
Do not breast-feed a baby while using leuprolide.
To make sure you can safely use leuprolide, tell your doctor if you have any of these other conditions:
FDA pregnancy category X. This medication can cause birth defects. Do not use leuprolide if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
Leuprolide usually causes women to stop ovulating or having menstrual periods. However, you may still be able to get pregnant. Use an effective barrier form of birth control (such as a condom or diaphragm with spermicide gel or inserts). Hormonal forms of contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective in preventing pregnancy while you are using leuprolide.
Because leuprolide is expected to cause your menstrual periods to stop, contact your doctor if your periods continue while you are being treated with this medication.
Long-term use of this medication may decrease bone density, possibly leading to osteoporosis. Talk with your doctor about your possible risk for osteoporosis. You may need to receive a bone scan if you ever need to be re-treated with leuprolide in the future.
How should I use leuprolide (Eligard, Lupron, Lupron Depot, Lupron Depot-Gyn, Lupron Depot-Ped)?
Leuprolide is injected under the skin or into a muscle. You may be shown how to use injections at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Leuprolide may be given once every month or once every 3 to 6 months. How often you receive this medication will depend on the condition being treated. Follow your doctor's instructions.
Because different brands or strengths of leuprolide are used to treat different conditions, it is very important that you receive exactly the brand and strength your doctor has prescribed. If you self-inject this medication at home, always check your medication to make sure you have received the correct brand and type prescribed by your doctor.
Your symptoms may become temporarily worse as your hormones adjust when you first start using this medication. For best results, keep using the medication as instructed by your doctor. Your condition should eventually improve with continued use of leuprolide.
To be sure this medication is helping your condition, your blood may need to be tested often. This will help your doctor determine how long to treat you with leuprolide. You may still need blood tests for up to 3 months after you stop using leuprolide to check your hormone levels and pituitary gland function. Do not miss any scheduled appointments.
Store Lupron in the original carton at room temperature, away from moisture and heat.
Store Eligard in the refrigerator. Do not freeze. You may take the medicine out and allow it to reach room temperature before mixing and injecting your dose. After the dose is mixed, you must use the injection within 30 minutes.
Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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