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Medications and Drugs

Brand Names: Xopenex, Xopenex Concentrate

Generic Name: levalbuterol inhalation (Pronunciation: leh val BYOO ter all)

What is levalbuterol inhalation (Xopenex, Xopenex Concentrate)?

Levalbuterol is a bronchodilator that relaxes muscles in the airways and increases air flow to the lungs.

Levalbuterol inhalation is used to treat or prevent bronchospasm in people with reversible obstructive airway disease.

Levalbuterol inhalation may also be used for purposes not listed in this medication guide.

What are the possible side effects of levalbuterol inhalation (Xopenex, Xopenex Concentrate)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • bronchospasm (wheezing, chest tightness, trouble breathing), especially after starting a new canister of this medicine;
  • chest pain and fast, pounding, or uneven heart beats;
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

  • headache, tremors, feeling anxious or nervous;
  • sleep problems (insomnia);
  • cough, runny or stuffy nose;
  • mild nausea, vomiting;
  • dry mouth and throat;
  • muscle pain; or
  • diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about levalbuterol inhalation (Xopenex, Xopenex Concentrate)?

You should not use this medication if you are allergic to levalbuterol or albuterol (Accuneb, ProAir, Proventil, Ventolin).

Before using levalbuterol, tell your doctor if you have heart disease, high blood pressure, congestive heart failure, a heart rhythm disorder, a seizure disorder, diabetes, or overactive thyroid.

Tell your doctor about all other medicines you use, especially heart or blood pressure medication, diuretics (water pills), antidepressants, or other inhaled bronchodilators.

Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing attacks. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor. An increased need for medication could be an early sign of a serious asthma attack.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

It is very important that you use nebulized levalbuterol properly, so that the medicine gets into the lungs. Talk to your doctor about proper nebulizer use.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of levalbuterol can be fatal.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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