Brand Names: Prinivil, Zestril

Generic Name: lisinopril (Pronunciation: lyse IN oh pril)

• What is lisinopril (Prinivil, Zestril)?
• What are the possible side effects of lisinopril (Prinivil, Zestril)?
• What is the most important information I should know about lisinopril (Prinivil, Zestril)?
• What should I discuss with my healthcare provider before taking lisinopril (Prinivil, Zestril)?
• How should I take lisinopril (Prinivil, Zestril)?
• What happens if I miss a dose (Prinivil, Zestril)?
• What happens if I overdose (Prinivil, Zestril)?
• What should I avoid while taking lisinopril (Prinivil, Zestril)?
• What other drugs will affect lisinopril (Prinivil, Zestril)?
• Where can I get more information?

What is lisinopril (Prinivil, Zestril)?

Lisinopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.

Lisinopril is used to treat high blood pressure (hypertension), congestive heart failure, and to improve survival after a heart attack.

Lisinopril may also be used for other purposes not listed in this medication guide.

Lisinopril 10 mg-EON

oval, pink, imprinted with E 101

Lisinopril 10 mg-GEN

round, white, imprinted with GP 113

Lisinopril 10 mg-MYL

round, white, imprinted with M, L 24

Lisinopril 10 mg-SAN

round, yellow, imprinted with LSP 10

Lisinopril 10 mg-TEV

round, red, imprinted with 93, 1113

Lisinopril 10 mg-WAT

round, blue, imprinted with WATSON 407

Lisinopril 2.5 mg-EON

oval, white, imprinted with E 25

Lisinopril 2.5 mg-GEN

round, white, imprinted with GP 111

Lisinopril 2.5 mg-MYL

round, blue, imprinted with M, L 22

Lisinopril 2.5 mg-SAN

round, yellow, imprinted with LSP 2 1/2

Lisinopril 2.5 mg-TEV

round, white, imprinted with 93, 1111

Lisinopril 2.5 mg-WAT

round, white, imprinted with WATSON, 405

Lisinopril 20 mg-APO

oval, brown, imprinted with APO, L20

Lisinopril 20 mg-EON

oval, pink, imprinted with E 102

Lisinopril 20 mg-GEN

round, pink, imprinted with GP 114

Lisinopril 20 mg-MYL

round, yellow, imprinted with M, L 25

Lisinopril 20 mg-TEV

oblong, red, imprinted with 93, 1114

Lisinopril 20 mg-WAT

round, yellow, imprinted with WATSON 408

Lisinopril 30 mg-EON

oval, pink, imprinted with E 103

Lisinopril 30 mg-GEN

round, peach, imprinted with GP 150

Lisinopril 30 mg-MYL

round, turquoise, imprinted with M, L 27

Lisinopril 30 mg-TEV

round, white, imprinted with 93, 5157

Lisinopril 30 mg-WAT

round, yellow, imprinted with WATSON 885

Lisinopril 40 mg-APO

oval, yellow, imprinted with APO, L40

Lisinopril 40 mg-EON

oval, yellow, imprinted with E 104

Lisinopril 40 mg-MYL

round, green, imprinted with M, L 26

Lisinopril 40 mg-RAN

round, yellow, imprinted with RX 535

Lisinopril 40 mg-TEV

oblong, white, imprinted with 93, 1115

Lisinopril 40 mg-WAT

round, yellow, imprinted with WATSON 409

Lisinopril 5 mg-EON

oval, pink, imprinted with E 54

Lisinopril 5 mg-GEN

round, pink, imprinted with GP 112

Lisinopril 5 mg-IVA

square, white, imprinted with 3758, Logo

Lisinopril 5 mg-MYL

round, peach, imprinted with M L 23

Lisinopril 5 mg-TEV

round, pink, imprinted with 93 1112

Lisinopril 5 mg-WAT

oblong, white, imprinted with WAT SON, 406

Prinivil 10 mg

shield, yellow, imprinted with MSD 106, PRINIVIL

Prinivil 20 mg

shield, pink, imprinted with PRINIVIL, MSD 207

Prinivil 40 mg

shield, pink, imprinted with PRINIVIL, MSD 237

Prinivil 5 mg

shield, white, imprinted with MSD 19, PRINIVIL

Zestril 10 mg

round, pink, imprinted with ZESTRIL 10, 131

Zestril 2.5 mg

round, white, imprinted with ZESTRIL 2 1/2, 135

Zestril 20 mg

round, pink, imprinted with ZESTRIL 20, 132

Zestril 30 mg

round, pink, imprinted with ZESTRIL 30, 133

Zestril 40 mg

round, yellow, imprinted with ZESTRIL 40, 134

Zestril 5 mg

oblong, pink, imprinted with ZESTRIL, 130

What are the possible side effects of lisinopril (Prinivil, Zestril)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• feeling light-headed, fainting;
• urinating more or less than usual, or not at all;
• fever, chills, body aches, flu symptoms;
• tired feeling, muscle weakness, and pounding or uneven heartbeats;
• chest pain; or
• swelling, rapid weight gain.

Less serious side effects may include:

• cough;
• dizziness, drowsiness, headache;
• nausea, vomiting, diarrhea, upset stomach; or
• mild skin itching or rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about lisinopril (Prinivil, Zestril)?

Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Lisinopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of lisinopril.

Do not use salt substitutes or potassium supplements while taking lisinopril, unless your doctor has told you to.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking lisinopril. Drink plenty of water each day while you are taking this medication.

What should I discuss with my healthcare provider before taking lisinopril (Prinivil, Zestril)?

Do not use this medication if you are allergic to lisinopril or to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before you take lisinopril, tell your doctor if you have:

• kidney disease (or if you are on dialysis);
• liver disease;
• heart disease or congestive heart failure;
• diabetes; or
• a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.

FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Lisinopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

It is not known whether lisinopril passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take lisinopril (Prinivil, Zestril)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Take each dose with a full glass of water.

Lisinopril can be taken with or without food.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking lisinopril. Drink plenty of water each day while you are taking this medication.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking lisinopril. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Store lisinopril at room temperature away from moisture and heat.

What happens if I miss a dose (Prinivil, Zestril)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Prinivil, Zestril)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling extremely dizzy or light-headed, or fainting.

What should I avoid while taking lisinopril (Prinivil, Zestril)?

Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of lisinopril.

Do not use salt substitutes or potassium supplements while taking lisinopril, unless your doctor has told you to.

What other drugs will affect lisinopril (Prinivil, Zestril)?

Before taking lisinopril, tell your doctor if you are taking any of the following drugs:

• gold injections to treat arthritis;
• lithium (Lithobid, Eskalith);
• gold injections, or aurothioglucose (Solganal);
• a potassium supplement such as K-Dur, Klor-Con;
• salt substitutes that contain potassium;
• insulin or diabetes medication you take by mouth;
• aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others; or
• a diuretic (water pill).

This list is not complete and there may be other drugs that can interact with lisinopril. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about lisinopril.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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Last Updated: April 12, 2009