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Medications and Drugs

Brand Names: Loxitane

Generic Name: loxapine (Pronunciation: LOX a peen)

What is loxapine (Loxitane)?

Loxapine is an antipsychotic medication. It affects the actions of chemicals in your brain.

Loxapine is used to treat schizophrenia.

Loxapine may also be used for purposes not listed in this medication guide.

Loxapine 10 mg-MYL

green/yellow, imprinted with MYLAN 7010

Loxapine 10 mg-WAT

white/yellow, imprinted with Watson 370, 10 mg

Loxapine 25 mg-MYL

green, imprinted with MYLAN 7025

Loxapine 25 mg-WAT

green/white, imprinted with Watson 371, 25 mg

Loxapine 5 mg-MYL

green, imprinted with MYLAN 7005

Loxapine 5 mg-WAT

white, imprinted with Watson 369, 5 mg

Loxapine 50 mg-MYL

blue/green, imprinted with MYLAN 7050

Loxapine 50 mg-WAT

blue/white, imprinted with Watson 372, 50 mg

What are the possible side effects of loxapine (Loxitane)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using loxapine and call your doctor at once if you have a serious side effect such as:

  • very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, feeling like you might pass out;
  • restless muscle movements in your eyes, tongue, jaw, or neck;
  • tremor (uncontrolled shaking);
  • trouble swallowing;
  • seizure (convulsions);
  • easy bruising or bleeding, unusual weakness;
  • fever, chills, body aches, flu symptoms;
  • vision changes;
  • severe constipation; or
  • urinating less than usual or not at all.

Less serious side effects may include:

  • dizziness or drowsiness;
  • blurred vision;
  • puffiness in your face;
  • feeling restless or agitated;
  • sleep problems (insomnia);
  • breast swelling or discharge;
  • changes in your menstrual periods;
  • nausea, vomiting, constipation;
  • changes in weight;
  • dry mouth, stuffy nose; or
  • mild skin rash, itching, or flaking.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about loxapine (Loxitane)?

Loxapine is not for use in psychotic conditions related to dementia. Loxapine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

You should not use this medication if you are allergic to loxapine, or if you have decreased alertness caused by taking certain medications or drinking alcohol.

Call your doctor at once if you have restless muscle movements in your eyes, tongue, jaw, or neck.

Loxapine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol. You should not take loxapine if you are under the effects of alcohol.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Loxapine can decrease perspiration and you may be more prone to heat stroke.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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