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What should I discuss with my healthcare provider before using lutropin alfa (Luveris)?

Lutropin alfa will not induce ovulation if the ovaries are not capable of producing an egg.

Before using this medication, tell your doctor if you

• might be pregnant;
• have a thyroid problem;
• have adrenal dysfunction;
• have cancer or a tumor of the breast, ovary, uterus, hypothalamus, or pituitary gland;
• have undiagnosed abnormal vaginal bleeding; or
• have ovarian cysts or enlargement not due to polycystic ovary disease (PCOD).

You may not be able to use lutropin alfa, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.

Treatment with lutropin alfa increases the likelihood of multiple births. Multiple births carry additional risk both for the mother and for fetuses. Discuss the risk of multiple births with your healthcare provider.

It is not known whether lutropin alfa passes into breast milk. Do not use lutropin alfa without first talking to your doctor if you are breast-feeding a baby.

How should I use lutropin alfa (Luveris)?

Use lutropin alfa exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

Lutropin alfa should only be administered subcutaneously. If you are administering this medication at home, your doctor will give you detailed instructions on how to mix the solution and give the injection. Do not inject this medication if you are not sure how.

Do not shake the vial, but gently swirl until the solution is clear. Do not inject any medication that is discolored or that has particles in it.

Never reuse a needle or syringe. Dispose of all needles and syringes in an appropriate, puncture-resistant disposal container.

Lutropin alfa should be used immediately after mixing. Any unused portion should be thrown away.

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