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mechlorethamine (cont.)

Who should not take mechlorethamine (Mustargen)?

Before taking mechlorethamine, tell your doctor if you

  • have had recent vaccinations;
  • have any type of infection;
  • have bone marrow problems;
  • have had radiation or x-ray therapy; or
  • have been treated with other cancer (chemotherapy) medicines.

You may not be able to take mechlorethamine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Mechlorethamine is in the FDA pregnancy category D. This means that mechlorethamine is known to cause birth defects in an unborn baby. Do not take mechlorethamine without first talking to your doctor if you are pregnant or could become pregnant during treatment. Contraceptive measures are recommended during treatment with mechlorethamine.

It is not known whether mechlorethamine passes into breast milk. Do not take mechlorethamine without first talking to your doctor if you are breast feeding a baby.

How should I take mechlorethamine (Mustargen)?

Mechlorethamine should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Your doctor will determine the correct amount and frequency of treatment with mechlorethamine depending upon the type of cancer being treated and other factors. Talk to your doctor if you have any questions or concerns regarding the treatment schedule.

Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with mechlorethamine to monitor progress and side effects.

Mechlorethamine is highly toxic and both the powder and solution must be handled with care. Inhalation of dust or vapors and contact with skin or mucous membranes (eyes, nose and mouth) must be avoided. Should accidental contact occur, rinse the area with water and seek emergency medical attention.

Your healthcare provider will store mechlorethamine as directed by the manufacturer.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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