Medications and Drugs
Brand Names: Depo-Provera, Depo-Provera Contraceptive, Depo-SubQ Provera 104
Generic Name: medroxyprogesterone (injectable) (Pronunciation: me DROX ee proe JES ter one)
What is medroxyprogesterone (Depo-Provera, Depo-Provera Contraceptive, Depo-SubQ Provera 104)?
Medroxyprogesterone is a form of progesterone, a female hormone that prevents ovulation (the release of an egg from an ovary). This medication also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.
Medroxyprogesterone is also used to ease pain and other symptoms in women with metastatic uterine or kidney cancer. This medication is not a cure for these conditions.
Medroxyprogesterone may also be used for purposes not listed in this medication guide.
What are the possible side effects of medroxyprogesterone (Depo-Provera, Depo-Provera Contraceptive, Depo-SubQ Provera 104)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about medroxyprogesterone (Depo-Provera, Depo-Provera Contraceptive, Depo-SubQ Provera 104)?
Medroxyprogesterone can cause birth defects. Do not use if this medication if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Also tell your doctor if you plan to become pregnant soon after you stop using medroxyprogesterone.
You should not use this medication if you are allergic to medroxyprogesterone, or if you have unusual vaginal bleeding, liver disease, or a history of breast cancer, heart attack, stroke, or blood clot.
Medroxyprogesterone may cause bone loss (osteoporosis) especially when used over long periods of time. Bone loss may not be reversible. Do not use this medication for longer than 2 years. Talk with your doctor about your specific risk of bone loss.
Medroxyprogesterone will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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