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What happens if I miss a dose (Lariam)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Lariam)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include stomach discomfort, vomiting, mouth sores, hair loss, easy bruising or bleeding, and peeling of the skin on your hands or feet.

What should I avoid while taking mefloquine (Lariam)?

Do not take halofantrine (Halfan) while you are taking mefloquine or just after you stop taking it. Serious, life-threatening side effects on your heart can occur if you take halofantrine before the mefloquine has cleared from your body.

Avoid taking chloroquine (Aralen Phosphate), quinine (Qualaquin) or quinidine (Quinaglute, Quinidex, Quin-Release) while you are taking mefloquine.

Mefloquine can cause side effects that may impair your thinking or reactions. Be careful if you drive, operate machinery, pilot an airplane, SCUBA dive, or do anything that requires you to be awake and alert.

What other drugs will affect mefloquine (Lariam)?

The following drugs can interact with mefloquine. Tell your doctor if you are using any of these:

• a blood thinner such as warfarin (Coumadin);
• ketoconazole (Nizoral);
• rifabutin (Mycobutin);
• rifampin (Rifadin, Rifater, Rifamate, Rimactane);
• tetracycline (Brodspec, Panmycin, Sumycin, Tetracap); or
• metoclopramide (Reglan).

This list is not complete and there may be other drugs that can interact with mefloquine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about mefloquine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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