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Medications and Drugs

Brand Names: Mebaral

Generic Name: mephobarbital (Pronunciation: MEF oh BAR bi tal)

What is mephobarbital (Mebaral)?

Mephobarbital is in a group of drugs called barbiturates (bar-BIT-chur-ates). Mephobarbital slows the activity of your brain and nervous system.

Mephobarbital is used as a sedative to treat anxiety, tension, and apprehension (dreading or feeling uneasy about what you think may happen). Mephobarbital is also used to treat seizures.

Mephobarbital may also be used for other purposes not listed in this medication guide.

Mebaral 100 mg

round, white, imprinted with M 33

Mebaral 32 mg

round, white, imprinted with M, 31

Mebaral 50 mg

round, white, imprinted with M, 32

Mephobarbital 100 mg-BRE

round, white, imprinted with B 418

Mephobarbital 50 mg-BRE

round, white, imprinted with B 417

What are the possible side effects of mephobarbital (Mebaral)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • confusion, hallucinations;
  • slow heart rate; or
  • feeling like you might pass out.

Less serious side effects may include:

  • dizziness;
  • memory or thinking problems;
  • feeling nervous or agitated;
  • nausea, vomiting; or
  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about mephobarbital (Mebaral)?

Do not take this medication if you are allergic to mephobarbital or to other barbiturates such as amobarbital (Amytal), butabarbital (Butisol), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton).

Before taking mephobarbital, tell your doctor if you have liver or kidney disease, anemia, heart disease, asthma or other breathing disorder, or a history of depression, mental illness, suicide attempt, or drug/alcohol addiction.

Do not use mephobarbital without telling your doctor if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.

Mephobarbital can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking mephobarbital.

Mephobarbital may be habit-forming and should be used only by the person it was prescribed for. Mephobarbital should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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