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What happens if I miss a dose (Solage)?

Skip the missed dose and wait until it is time for your next dose to apply the medicine. Do not use extra medicine to make up the missed dose.

What happens if I overdose (Solage)?

Seek emergency medical attention if you think you have used too much of this medicine.

Mequinol and tretinoin applied to the skin is not expected to cause overdose symptoms.

What should I avoid while using mequinol and tretinoin topical (Solage)?

You must avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Mequinol and tretinoin topical can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

If you get a sunburn, you may need to wait until it heals before you can use mequinol and tretinoin.

Mequinol and tretinoin topical is for use only on the skin. Avoid getting this medication in your eyes, mouth, or along the creases of your nose. If it does get into these areas, wash with water.

Do not use mequinol and tretinoin on sunburned, windburned, dry, chapped, irritated, or broken skin. Also avoid using this medication in wounds or on areas of eczema. Wait until these conditions have healed before using mequinol and tretinoin.

Your skin may be more sensitive to weather extremes such as cold and wind. Protect your skin with clothing.

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Do not use other medicated skin products unless your doctor has told you to.

What other drugs will affect mequinol and tretinoin topical (Solage)?

Taking certain medications can worsen your risk of severe sunburn if you are also applying mequinol and tretinoin topical. Before applying this medication, Tell your doctor if you are taking any of the following drugs:

• a sulfa drug such as Bactrim, Cotrim, Septra, Gantrisin, and others;
• a diuretic (water pill) such as chlorothiazide (Diuril), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Lopressor, Vasoretic, Zestoretic), chlorthalidone (Hygroton, Thalitone), indapamide (Lozol), metolazone (Mykrox, Zaroxolyn), and others;
• a tetracycline antibiotic such as doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), tetracycline (Brodspec, Panmycin, Sumycin, Tetracap), and others;
• a fluoroquinolone antibiotics such as enoxacin (Penetrex), lomefloxacin (Maxaquin), ciprofloxacin (Cipro), norfloxacin (Noroxin), or ofloxacin (Floxin), and others; or
• a phenothiazine such as chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), prochlorperazine (Compazine), thioridazine (Mellaril), or trifluperazine (Stelazine).

This list is not complete and there may be other drugs that can interact with mequinol and tretinoin topical. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about mequinol and tretinoin topical.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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