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Medications and Drugs

Brand Names: Skelaxin

Generic Name: metaxalone (Pronunciation: me TAX a lone)

What is metaxalone (Skelaxin)?

Metaxalone is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) in the brain.

Metaxalone is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

Metaxalone may also be used for other purposes not listed in this medication guide.

Skelaxin 800 mg

oblong, pink, imprinted with 86 67, S

What are the possible side effects of metaxalone (Skelaxin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using metaxalone and call your doctor at once if you have any of these serious side effects:

  • nausea, stomach pain, loss of appetite;
  • low fever;
  • dark urine, clay-colored stools; or
  • jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • drowsiness, dizziness;
  • feeling nervous or irritable;
  • headache;
  • mild nausea, vomiting, upset stomach; or
  • skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about metaxalone (Skelaxin)?

Do not use this medication if you are allergic to metaxalone, or if you have anemia (a lack of red blood cells), or severe kidney or liver disease.

Before using metaxalone, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease. You may need a dose adjustment or special tests to safely take metaxalone.

Metaxalone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of metaxalone.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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