IN THIS ARTICLE
- What is methadone (Diskets, Dolophine, Methadose)?
- What are the possible side effects of methadone (Diskets, Dolophine, Methadose)?
- What is the most important information I should know about methadone (Diskets, Dolophine, Methadose)?
- What should I discuss with my healthcare provider before using methadone (Diskets, Dolophine, Methadose)?
- How should I use methadone (Diskets, Dolophine, Methadose)?
- What happens if I miss a dose (Diskets, Dolophine, Methadose)?
- What happens if I overdose (Diskets, Dolophine, Methadose)?
- What should I avoid while using methadone (Diskets, Dolophine, Methadose)?
- What other drugs will affect methadone (Diskets, Dolophine, Methadose)?
- Where can I get more information?
What happens if I miss a dose (Diskets, Dolophine, Methadose)?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
If you miss your doses for longer than 3 days in a row, call your doctor for instructions. You may need to restart methadone at a lower dose.
What happens if I overdose (Diskets, Dolophine, Methadose)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of methadone can be fatal, especially if you take it with alcohol or other narcotic medications.
Overdose symptoms may include extreme drowsiness, pinpoint pupils, confusion, cold and clammy skin, weak pulse, shallow breathing, fainting, or breathing that stops.
What should I avoid while using methadone (Diskets, Dolophine, Methadose)?
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
What other drugs will affect methadone (Diskets, Dolophine, Methadose)?
Do not use methadone with other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.
Do not use methadone with any of the following drugs without first talking to your doctor:
- a diuretic (water pill);
- antibiotics such as azithromycin (Zithromax), ciprofloxacin (Cipro), clarithromycin (Biaxin), erythromycin (E-Mycin, Ery-Tab), itraconazole (Sporanox), ketoconazole (Nizoral), metronidazole (Flagyl) or voriconazole (Vfend);
- heart or blood pressure medication such as diltiazem (Cardizem, Dilacor, Tiazac) or verapamil (Calan, Covera, Isoptin, Verelan);
- HIV medicines such as abacavir (Ziagen), amprenavir (Agenerase), didanosine (Videx), efavirenz (Sustiva), lopinavir/ritonavir (Kaletra), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir), stavudine (Zerit), or zidovudine (Retrovir);
- an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);
- other narcotic medications such as pentazocine (Talwin), nalbuphine (Nubain), buprenorphine (Subutex), or butorphanol (Stadol);
- rifampin (Rifadin, Rimactane, Rifater); or
- seizure medication such as phenobarbital (Luminal, Solfoton) or phenytoin (Dilantin).
This list is not complete and there are many other drugs that can interact with Methadone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about methadone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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