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What happens if I miss a dose (Methergine)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Methergine)?

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a methylergonovine overdose may include nausea, vomiting, stomach pain, numbness or tingling, muscle twitching, feeling light-headed, fainting, shallow breathing, coldness, or seizure (convulsions).

What should I avoid while receiving methylergonovine (Methergine)?

Grapefruit and grapefruit juice may interact with methylergonovine. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

What other drugs will affect methylergonovine (Methergine)?

Before taking methylergonovine, tell your doctor if you are using any of the following drugs:

• zileuton (Zyflo);
• antibiotics such as erythromycin (Ery-Tab, Erythrocin, E.E.S), clarithromycin (Biaxin), troleandomycin (Tao);
• fluoxetine (Prozac), fluvoxamine (Luvox);
• clotrimazole (Mycelex Troche), fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), voriconazole (Vfend);
• other ergot medicines such as methysergide (Sansert), ergotamine (Ergostat, Medihaler, Cafergot, Ercaf, Wigraine), or dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray); or
• HIV medicines such as delaviridine (Rescriptor), indinavir (Crixivan), ritonavir (Norvir), saquinavir (Invirase), or nelfinavir (Viracept).

If you are using any of these drugs, you may not be able to use methylergonovine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect methylergonovine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has more information about methylergonovine written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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